2015年于76net必赢官网生物治疗全国重点实验室毕业，获理学博士学位，随后在76net必赢官网生物治疗全国重点实验室从事博士后研究；现任76net必赢官网华西基础医学76net必赢官网研究员。2013年作为访问学者赴澳大利亚Monash University学习交流1年。

共发表论文60余篇。其中，以第一作者或通讯作者（含共同）在Nat Commun (2篇)、Trends Biochem Sci、Autophagy (5篇)、Hepatology、Cancer Res、STTT、Med Res Rev、Redox Biol等期刊发表论文35篇，其中14篇IF＞10分。被Cell、Nat Rev Drug Discov等期刊引用2600余次，其中3篇被引超过200次，单篇最高被引411次，H-index为35。任Cancer Metab副主编，Expert Rev Proteomics、Malignancy Spectrum 编委，Antioxidants、Life客座编辑；Lancet Reg Health-Eu、STTT、Oncogene、Cell Chem Biol、BBA-Rev Cancer、Mol Cancer、EBioMedicine等期刊审稿人。

主持国家自然科学基金面上项目（4项）、青年基金和中国博士后科学基金特别资助项目等，作为项目骨干参与国家自然科学基金重大和重点项目。获教育部自然科学奖一等奖（排名4/11）、76net必赢官网学术新人奖、76net必赢官网青年科技人才奖、76net必赢官网好未来优秀学者奖、76net必赢官网优秀科研人才奖；入选76net必赢官网双百人才工程B计划、四川省学术和技术带头人后备人选、四川省卫生健康委员会学术技术带头人后备人选、76net必赢官网青年科技学术带头人培育项目。

讲授《科研素养与创新能力培养》、《开放式医学创新论坛》等课程；指导大创项目10余项，其中3项获国家级立项，1 项获省级立项，1项结题优秀；大创成果在国际学术刊物发表论文4篇（本科生均为论文一作）；连续被评为76net必赢官网大学生创新创业与实践教育优秀指导教师（2019、2020）。

【研究方向】

1. 肿瘤代谢与氧化还原信号调控

2. 抗肿瘤药物靶点的鉴定和作用机制

【代表性论文】

1. Luo L, Wu X, Fan J, Dong L, Wang M, Zeng Y, Li S, Yang W, Jiang J, Wang K. FBXO7 Ubiquitinates PRMT1 to Suppress Serine Synthesis and Tumor Growth in Hepatocellular Carcinoma. Nat Commun. 2024;15(1):4790.

2. Wang K, Luo L, Fu S, Wang M, Wang Z, Dong L, Wu X, Dai L, Peng Y, Shen G, Chen HN, Nice EC, Wei X, Huang C. PHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma. Nat Commun. 2023;14(1):1011.

3. Mu B, Zeng Y, Luo L, Wang K. Oxidative Stress-mediated Protein Sulfenylation in Human Diseases: Past, Present, and Future. Redox Biol. 2024;76:103332.

4. Dong L, Luo L, Wang Z, Lian S, Wang M, Wu X, Fan J, Zeng Y, Li S, Lv S, Yang Y, Chen R, Shen E, Yang W, Li C, Wang K. Targeted degradation of NDUFS1 by agrimol B promotes mitochondrial ROS accumulation and cytotoxic autophagy arrest in hepatocellular carcinoma. Free Radic Biol Med. 2024; 220:111-24.

5. Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B. Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy. Autophagy. 2023;19(12):3132-50 (一作和共同通讯).

6. Dong L, He J, Luo L, Wang K. Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals. Pharmaceuticals. 2023;16(1):92. (ESI高被引论文)

7. Jiang J, Peng L, Wang K, Huang C. Moonlighting Metabolic Enzymes in Cancer: New Perspectives on the Redox Code. Antioxid Redox Signal. 2021; 34(13):979-1003 (共同通讯) .

8. Jiang J, Zhang L, Chen H, Lei Y, Zhang T, Wang Y, Jin P, Lan J, Zhou L, Huang Z, Li B, Liu Y, Gao W, Xie K, Zhou L, Nice EC, Peng Y, Cao Y, Wei Y, Wang K, Huang C. Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma. Autophagy. 2020;16(1):106-22 (共同通讯).

9. Huang Z, Zhou JK, Wang K, Chen H, Qin S, Liu J, Luo M, Chen Y, Jiang J, Zhou L, Zhu L, He J, Li J, Pu W, Gong Y, Li J, Ye Q, Dong D, Hu H, Zhou Z, Dai L, Wei Y, Huang C, Wei X, Peng Y. PDLIM1 inhibits tumor metastasis through activating Hippo signaling in hepatocellular carcinoma. Hepatology. 2020;71(5):1643-59 (共同一作).

10. Wang K, Jiang J, Lei Y, Zhou S, Wei Y, Huang C. Targeting Metabolic-Redox Circuits for Cancer Therapy. Trends Biochem Sci. 2019;44(5):401-14 (ESI高被引论文) .

11. Wang K, Zhang T, Lei Y, Li X, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Nice EC, Wu M, Huang C, Wei Y. Identification of ANXA2 (annexin A2) as a Specific Bleomycin Target to Induce Pulmonary Fibrosis by Impeding TFEB-mediated Autophagic Flux. Autophagy. 2018;14(2):269-82.

12. Jiang J, Wang K, Chen Y, Chen H, Nice EC, Huang C. Redox regulation in tumor cell epithelial-mesenchymal transition: Molecular basis and therapeutic strategy. Signal Transduct Target Ther. 2017;2:e17036 (共同一作) .

13. Wang K, Gao W, Dou Q, Chen H, Li Q, Nice EC, Huang C. Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer. Autophagy. 2016;12(12):2498-9.

14. Dou Q, Chen HN, Wang K, Yuan K, Lei Y, Li K, Lan J, Chen Y, Huang Z, Xie N, Zhang L, Xiang R, Nice EC, Wei Y, Huang C. Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer. Cancer Res. 2016;76(15):4457-69. (共同一作).

15. Lei Y, Wang K, Deng L, Chen Y, Nice EC, Huang C. Redox Regulation of Inflammation: Old Elements, a New Story. Med Res Rev. 2015;35(2):306-40. (共同一作).